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KMID : 0352019920170010113
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Kyung Hee University Medical Journal
1992 Volume.17 No. 1 p.113 ~ p.122
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Histologic Study of Lymph Follicles and Germinal Centers in the Popliteal Lymph Nodes of the ICR and C3H/He Mice
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한상인
이원규/허영범/김정혜/안희경
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Abstract
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This study was aimed to clarify the distribution of lymph follicles, germinal centers and deep cortex structure in the lymph nodes of the ICR and C3H/He strain mice. Male adult mice were adopted in this study. After mice were sacrifed, the right
popliteal lymph nodes were removed in the popliteal fossa and fixed in Zenker-formol solution for 3 hours and embedded in plastic resin. The cutting thickness was 3μm serially and one of every two section was stained in May-Grunwald and Giemsa
solution.
@ES The results obtained from this study were as follows ;
@EN 1. The size of lymph follicle was 0.727mm in ICR mice and 0.765mm in C3H/He mice.
2. The average number of lymph follicles per popliteal lymph node was 11.25 in ICR mice, but 15 in C3H/He mice. The major of the lymph follicles situated in peripheral cortex overlaying the deep cortex unit (PCOU). The lymph follicles in PCOU
was
82%
in ICR, 80% in C3H/H3 mice.
3. The most transverse diameters of each strain lymph follicles was between 0.01 to 0.19mm.
4. The characteristic difference was number of germinal centers, C3H/He mice lymph follicles contained germinal centers in 59.95%, but ICR mice lymph follicles contained it in 3%.
5. The morphology of deep cortex was not significant between each strain.
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KEYWORD
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